1qhf: Difference between revisions

New page: left|200px<br /><applet load="1qhf" size="450" color="white" frame="true" align="right" spinBox="true" caption="1qhf, resolution 1.7Å" /> '''YEAST PHOSPHOGLYCERAT...
 
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[[Image:1qhf.jpg|left|200px]]<br /><applet load="1qhf" size="450" color="white" frame="true" align="right" spinBox="true"  
[[Image:1qhf.jpg|left|200px]]<br /><applet load="1qhf" size="350" color="white" frame="true" align="right" spinBox="true"  
caption="1qhf, resolution 1.7&Aring;" />
caption="1qhf, resolution 1.7&Aring;" />
'''YEAST PHOSPHOGLYCERATE MUTASE-3PG COMPLEX STRUCTURE TO 1.7 A'''<br />
'''YEAST PHOSPHOGLYCERATE MUTASE-3PG COMPLEX STRUCTURE TO 1.7 A'''<br />


==Overview==
==Overview==
The crystal structure of the tetrameric glycolytic enzyme phosphoglycerate, mutase from the yeast Saccharomyces cerevisiae has been determined to 1.7, A resolution in complex with the sugar substrate. The difference map, indicates that 3-phosphoglycerate is bound at the base of a 12 A cleft, positioning C2 of the substrate within 3.5 A of the primary catalytic, residue, histidine 8.
The crystal structure of the tetrameric glycolytic enzyme phosphoglycerate mutase from the yeast Saccharomyces cerevisiae has been determined to 1.7 A resolution in complex with the sugar substrate. The difference map indicates that 3-phosphoglycerate is bound at the base of a 12 A cleft, positioning C2 of the substrate within 3.5 A of the primary catalytic residue, histidine 8.


==About this Structure==
==About this Structure==
1QHF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with SO4 and 3PG as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phosphoglycerate_mutase Phosphoglycerate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.1 5.4.2.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QHF OCA].  
1QHF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=3PG:'>3PG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phosphoglycerate_mutase Phosphoglycerate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.1 5.4.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHF OCA].  


==Reference==
==Reference==
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[[Category: Crowhurst, G.]]
[[Category: Crowhurst, G.]]
[[Category: Littlechild, J.]]
[[Category: Littlechild, J.]]
[[Category: Watson, H.C.]]
[[Category: Watson, H C.]]
[[Category: 3PG]]
[[Category: 3PG]]
[[Category: SO4]]
[[Category: SO4]]
[[Category: transferase (phosphoryl)]]
[[Category: transferase (phosphoryl)]]


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