Tripeptidyl peptidase: Difference between revisions

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[[Image:2d5l.png|left|200px|thumb|Crystal Structure of Tripeptidyl peptidase ([[2d5l]])]]
[[Image:2d5l.png|left|200px|thumb|Crystal Structure of Tripeptidyl peptidase ([[2d5l]])]]
{{STRUCTURE_2d5l|  PDB=2d5l | SIZE=300| SCENE=Tripeptidyl_peptidase/Cv/1 |right|CAPTION=Tripeptidyl peptidase [[2d5l]]}}
{{STRUCTURE_3ee6|  PDB=3ee6 | SIZE=400| SCENE= |right|CAPTION=Tripeptidyl peptidase [[3ee6]]}}


[[Tripeptidyl peptidase]] (TPP) is an enzyme which cleaves N-terminal tripeptides from polypeptides.  TPP-I functions in lysosomes, TPP-II is part of the ubiquitin-proteasome pathway. The images at the left and at the right correspond to one representative TPP, ''i.e.'' the crystal structure of Pro-Tripeptidyl peptidase-IV from ''Porphyromonas gingivalis'' ([[2d5l]]).
[[Tripeptidyl peptidase]] (TPP) is an enzyme which cleaves N-terminal tripeptides from polypeptides.  TPP-I functions in lysosomes, TPP-II is part of the ubiquitin-proteasome pathway. The images at the left and at the right correspond to one representative TPP, ''i.e.'' the crystal structure of Pro-Tripeptidyl peptidase-IV from ''Porphyromonas gingivalis'' ([[2d5l]]).

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Alexander Berchansky, Michal Harel, Joel L. Sussman