Recoverin, a calcium-activated myristoyl switch: Difference between revisions
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{{STRUCTURE_2d8n| right| PDB=2d8n | SCENE=|CAPTION= Human Ras GTPase activating protein dimer. SH3 domain, [[2d8n]] }} | |||
<applet load='Recoverin_linear_morph14.pdb' scene='Recoverin,_a_calcium-activated_myristoyl_switch/Recoverin_morph/2' size='300' frame='true' align='right' caption='Recoverin: [[1iku]] model 7 morphed to [[1jsa]] model 9.' /> | <applet load='Recoverin_linear_morph14.pdb' scene='Recoverin,_a_calcium-activated_myristoyl_switch/Recoverin_morph/2' size='300' frame='true' align='right' caption='Recoverin: [[1iku]] model 7 morphed to [[1jsa]] model 9.' /> | ||
==Function== | ==Function== | ||
Recoverin is a 23 kD protein that regulates recovery of the eye from exposure to light, and the adaptation to background light. Recoverin controls the lifetime of photoactivated rhodopsin. Recoverin in turn is regulated by calcium ions, which cause recoverin molecules to associate with the disc membranes which fill the photosensitive portion of the rod cells in the eye, rather than diffusing freely in the cytosol. | '''Recoverin''' is a 23 kD protein that regulates recovery of the eye from exposure to light, and the adaptation to background light. Recoverin controls the lifetime of photoactivated rhodopsin. Recoverin in turn is regulated by calcium ions, which cause recoverin molecules to associate with the disc membranes which fill the photosensitive portion of the rod cells in the eye, rather than diffusing freely in the cytosol. | ||
{{Clear}} | {{Clear}} | ||