Neuroligin: Difference between revisions
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[[Neuroligin|Neuroligins]] (NLGN) are a family of postsynaptic proteins which bind to the presynaptic [[Neurexin]] (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4 | [[Neuroligin|Neuroligins]] (NLGN) are a family of postsynaptic proteins which bind to the presynaptic [[Neurexin]] (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4. | ||
For Structural Analysis of Neuroligin, See: [[Neuroligin-Neurexin Interaction]] | For Structural Analysis of Neuroligin, See: [[Neuroligin-Neurexin Interaction]] | ||
Revision as of 13:04, 8 November 2012
Neuroligins (NLGN) are a family of postsynaptic proteins which bind to the presynaptic Neurexin (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4.
For Structural Analysis of Neuroligin, See: Neuroligin-Neurexin Interaction
3D Structures of Neuroligin3D Structures of Neuroligin
NLGNNLGN
3bl8 - mNLGN-2 cholinesterase domain – mouse
3be8 - hNLGN-4 cholinesterase domain – human
3bix - rNLGN-1 cholinesterase domain - rat
NLGN+NRXNNLGN+NRXN
2xb6, 2wqz – hNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3b3q - mNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3biw - rNLGN-1 cholinesterase domain+NRXN-1β LNS domain