1e50: Difference between revisions

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{{Seed}}
[[Image:1e50.png|left|200px]]
[[Image:1e50.png|left|200px]]


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{{STRUCTURE_1e50|  PDB=1e50  |  SCENE=  }}  
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===AML1/CBF COMPLEX===
===AML1/CBF COMPLEX===


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{{ABSTRACT_PUBMED_10856244}}
{{ABSTRACT_PUBMED_10856244}}
==Disease==
Known disease associated with this structure: Leukemia, acute myeloid OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Platelet disorder, familial, with associated myeloid malignancy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Rheumatoid arthritis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Myeloid leukemia, acute, M4Eo subtype OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=121360 121360]]


==About this Structure==
==About this Structure==
1E50 is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E50 OCA].  
[[1e50]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E50 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:10856244</ref><references group="xtra"/>
<ref group="xtra">PMID:010856244</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bravo, J.]]
[[Category: Bravo, J.]]
Line 32: Line 17:
[[Category: Warren, A J.]]
[[Category: Warren, A J.]]
[[Category: Williams, R L.]]
[[Category: Williams, R L.]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Transcription factor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 22:09:15 2009''

Revision as of 12:59, 31 October 2012

File:1e50.png

Template:STRUCTURE 1e50

AML1/CBF COMPLEXAML1/CBF COMPLEX

Template:ABSTRACT PUBMED 10856244

About this StructureAbout this Structure

1e50 is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Warren AJ, Bravo J, Williams RL, Rabbitts TH. Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta. EMBO J. 2000 Jun 15;19(12):3004-15. PMID:10856244 doi:10.1093/emboj/19.12.3004

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