1pho: Difference between revisions
New page: left|200px<br /><applet load="1pho" size="450" color="white" frame="true" align="right" spinBox="true" caption="1pho, resolution 3.0Å" /> '''CRYSTAL STRUCTURES EX... |
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[[Image:1pho.gif|left|200px]]<br /><applet load="1pho" size=" | [[Image:1pho.gif|left|200px]]<br /><applet load="1pho" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1pho, resolution 3.0Å" /> | caption="1pho, resolution 3.0Å" /> | ||
'''CRYSTAL STRUCTURES EXPLAIN FUNCTIONAL PROPERTIES OF TWO E. COLI PORINS'''<br /> | '''CRYSTAL STRUCTURES EXPLAIN FUNCTIONAL PROPERTIES OF TWO E. COLI PORINS'''<br /> | ||
==Overview== | ==Overview== | ||
Porins form aqueous channels that aid the diffusion of small hydrophilic | Porins form aqueous channels that aid the diffusion of small hydrophilic molecules across the outer membrane of Gram-negative bacteria. The crystal structures of matrix porin and phosphoporin both reveal trimers of identical subunits, each subunit consisting of a 16-stranded anti-parallel beta-barrel containing a pore. A long loop inside the barrel contributes to a constriction of the channel where the charge distribution affects ion selectivity. The structures explain at the molecular level functional characteristics and their alterations by known mutations. | ||
==About this Structure== | ==About this Structure== | ||
1PHO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http:// | 1PHO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PHO OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Cowan, S | [[Category: Cowan, S W.]] | ||
[[Category: Jansonius, J | [[Category: Jansonius, J N.]] | ||
[[Category: Schirmer, T.]] | [[Category: Schirmer, T.]] | ||
[[Category: outer membrane protein]] | [[Category: outer membrane protein]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:28:52 2008'' | ||
