Factor XIII: Difference between revisions
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[[Image:1ggt.png|left|200px|thumb|Crystal Structure of human Factor XIII, [[1ggt]]]] | [[Image:1ggt.png|left|200px|thumb|Crystal Structure of human Factor XIII, [[1ggt]]]] | ||
{{STRUCTURE_1ggt| PDB=1ggt | SIZE=300| SCENE=Factor_XIII/Cv/1 |right|CAPTION=Human Factor XIII, [[1ggt]] }} | {{STRUCTURE_1ggt| PDB=1ggt | SIZE=300| SCENE=Factor_XIII/Cv/1 |right|CAPTION=Human Factor XIII dimer, [[1ggt]] }} | ||
[[Factor XIII]] (FXIII) belongs to the blood coagulation system and crosslinks fibrin resulting in an insoluble clot. FXIII is activated by thrombin which cleaves it and releases an activation peptide. The images at the left and at the right correspond to one representative FXIII, ''i.e.'' the crystal structure of human Factor XIII ([[1ggt]]). | [[Factor XIII]] (FXIII) belongs to the blood coagulation system and crosslinks fibrin resulting in an insoluble clot. FXIII is activated by thrombin which cleaves it and releases an activation peptide. The images at the left and at the right correspond to one representative FXIII, ''i.e.'' the crystal structure of human Factor XIII ([[1ggt]]). | ||
Revision as of 15:13, 30 October 2012
Factor XIII (FXIII) belongs to the blood coagulation system and crosslinks fibrin resulting in an insoluble clot. FXIII is activated by thrombin which cleaves it and releases an activation peptide. The images at the left and at the right correspond to one representative FXIII, i.e. the crystal structure of human Factor XIII (1ggt).
3D Structures of Factor XIII3D Structures of Factor XIII
1ggt – hFXIII - human
1ex0 – hFXIII zymogen (mutant)
1fie – hFXIII subunit A
1f13 - hFXIII zymogen subunit A dimmer
1ggy, 1qrk, 1ggu, 1evu – hFXIII + ion
1de7 – fFXIII activation peptide + α-thrombin