Group:MUZIC:CARP: Difference between revisions

No edit summary
No edit summary
Line 21: Line 21:
==CARP Interactions==
==CARP Interactions==


CARP/Ankrd1 binds the sarcomeric protein titin <ref name='one'>PMID 14583192</ref> and cardiac calsequestrin-2, CASQ2. <ref name='eight'>PMID 15698842</ref> These interactions are mediated, at least partially, by the binding sites localized within the ankyrin repeats and coiled-coil domain. Ankrd1 can also interact with the sarcomeric proteins myopalladin <ref name='twenty three'>PMID 11309420</ref>., desmin <ref name='twenty four'>PMID 16450059</ref>, and muscle-specific RING finger proteins MuRF1/MuRF2 <ref name='twenty five'>PMID 18157088</ref> indicating its structural role. CARP/Ankrd1 also binds calpain 3 <ref name='twenty one'>PMID 20860623</ref> and several transcription factors such as YB1 and p53.
CARP/Ankrd1 binds the sarcomeric protein cardiac calsequestrin-2, CASQ2. <ref name='eight'>PMID 15698842</ref> These interactions are mediated, at least partially, by the binding sites localized within the ankyrin repeats and coiled-coil domain. Ankrd1 can also interact with the sarcomeric proteins myopalladin <ref name='twenty three'>PMID 11309420</ref>., desmin <ref name='twenty four'>PMID 16450059</ref>, and muscle-specific RING finger proteins MuRF1/MuRF2 <ref name='twenty five'>PMID 18157088</ref> indicating its structural role. CARP/Ankrd1 also binds calpain 3 <ref name='twenty one'>PMID 20860623</ref> and several transcription factors such as YB1 and p53.


== Refrences ==
== Refrences ==
<references/>
<references/>