Colicin I receptor: Difference between revisions

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   {{STRUCTURE_2hdi|  PDB=2hdi  | SIZE=400| SCENE= |right|CAPTION=E. coli colicin I receptor complexed with colicin Ia receptor-binding domain and lauryl dimethylamine oxide, [[2hdi]] }}
   {{STRUCTURE_2hdi|  PDB=2hdi  | SIZE=400| SCENE= |right|CAPTION=E. coli colicin I receptor (grey) complexed with colicin Ia receptor-binding domain (green) and lauryl dimethylamine oxide, [[2hdi]] }}


'''Colicin I receptor''' (Cir) is an E. coli outer membrane protein which binds [[Colicin|colicin]] Ia.  Upon binding it changes its conformation enabling the colicin to insert into the inner membrane forming a voltage-dependent ion channel resulting in killing the bacteria.
'''Colicin I receptor''' (Cir) is an E. coli outer membrane protein which binds [[Colicin|colicin]] Ia.  Upon binding it changes its conformation enabling the colicin to insert into the inner membrane forming a voltage-dependent ion channel resulting in killing the bacteria.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky