1c2t: Difference between revisions

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m Protected "1c2t" [edit=sysop:move=sysop]
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[[Image:1c2t.png|left|200px]]
[[Image:1c2t.png|left|200px]]


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{{STRUCTURE_1c2t|  PDB=1c2t  |  SCENE=  }}  
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===NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLASE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.===
===NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLASE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.===


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{{ABSTRACT_PUBMED_10606510}}
{{ABSTRACT_PUBMED_10606510}}


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==Reference==
==Reference==
<ref group="xtra">PMID:10606510</ref><references group="xtra"/>
<ref group="xtra">PMID:010606510</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Phosphoribosylglycinamide formyltransferase]]
[[Category: Phosphoribosylglycinamide formyltransferase]]
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[[Category: Wilson, I A.]]
[[Category: Wilson, I A.]]
[[Category: Yamashita, M M.]]
[[Category: Yamashita, M M.]]
[[Category: Anti-cancer agent]]
[[Category: Inhibitor complex]]
[[Category: Purine biosynthesis]]
[[Category: Transferase]]

Revision as of 22:56, 21 October 2012

File:1c2t.png

Template:STRUCTURE 1c2t

NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLASE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLASE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.

Template:ABSTRACT PUBMED 10606510

About this StructureAbout this Structure

1c2t is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Greasley SE, Yamashita MM, Cai H, Benkovic SJ, Boger DL, Wilson IA. New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid. Biochemistry. 1999 Dec 21;38(51):16783-93. PMID:10606510

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