1a5a: Difference between revisions

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[[Image:1a5a.png|left|200px]]
[[Image:1a5a.png|left|200px]]


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{{STRUCTURE_1a5a|  PDB=1a5a  |  SCENE=  }}  
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===CRYO-CRYSTALLOGRAPHY OF A TRUE SUBSTRATE, INDOLE-3-GLYCEROL PHOSPHATE, BOUND TO A MUTANT (ALPHAD60N) TRYPTOPHAN SYNTHASE ALPHA2BETA2 COMPLEX REVEALS THE CORRECT ORIENTATION OF ACTIVE SITE ALPHA GLU 49===
===CRYO-CRYSTALLOGRAPHY OF A TRUE SUBSTRATE, INDOLE-3-GLYCEROL PHOSPHATE, BOUND TO A MUTANT (ALPHAD60N) TRYPTOPHAN SYNTHASE ALPHA2BETA2 COMPLEX REVEALS THE CORRECT ORIENTATION OF ACTIVE SITE ALPHA GLU 49===


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[[Category: Rhee, S.]]
[[Category: Rhee, S.]]
[[Category: Carbon-oxygen lyase]]
[[Category: Carbon-oxygen lyase]]
[[Category: Lyase]]

Revision as of 17:22, 21 October 2012

File:1a5a.png

Template:STRUCTURE 1a5a

CRYO-CRYSTALLOGRAPHY OF A TRUE SUBSTRATE, INDOLE-3-GLYCEROL PHOSPHATE, BOUND TO A MUTANT (ALPHAD60N) TRYPTOPHAN SYNTHASE ALPHA2BETA2 COMPLEX REVEALS THE CORRECT ORIENTATION OF ACTIVE SITE ALPHA GLU 49CRYO-CRYSTALLOGRAPHY OF A TRUE SUBSTRATE, INDOLE-3-GLYCEROL PHOSPHATE, BOUND TO A MUTANT (ALPHAD60N) TRYPTOPHAN SYNTHASE ALPHA2BETA2 COMPLEX REVEALS THE CORRECT ORIENTATION OF ACTIVE SITE ALPHA GLU 49

Template:ABSTRACT PUBMED 9535826

About this StructureAbout this Structure

1a5a is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhimurium. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Rhee S, Miles EW, Davies DR. Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant (alphaD60N) tryptophan synthase alpha2beta2 complex reveals the correct orientation of active site alphaGlu49. J Biol Chem. 1998 Apr 10;273(15):8553-5. PMID:9535826
  2. ↑ Rhee S, Miles EW, Mozzarelli A, Davies DR. Cryocrystallography and microspectrophotometry of a mutant (alpha D60N) tryptophan synthase alpha 2 beta 2 complex reveals allosteric roles of alpha Asp60. Biochemistry. 1998 Jul 28;37(30):10653-9. PMID:9692955 doi:10.1021/bi980779d

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