3eig: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3eig]] is a 1 chain structure | [[3eig]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EIG OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 00:55, 21 October 2012
Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductaseCrystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase
Template:ABSTRACT PUBMED 19478082
About this StructureAbout this Structure
3eig is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Volpato JP, Yachnin BJ, Blanchet J, Guerrero V, Poulin L, Fossati E, Berghuis AM, Pelletier JN. Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance. J Biol Chem. 2009 Jul 24;284(30):20079-89. Epub 2009 May 28. PMID:19478082 doi:10.1074/jbc.M109.018010