1nik: Difference between revisions
New page: left|200px<br /><applet load="1nik" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nik, resolution 4.10Å" /> '''Wild Type RNA Polyme... |
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[[Image:1nik.gif|left|200px]]<br /><applet load="1nik" size=" | [[Image:1nik.gif|left|200px]]<br /><applet load="1nik" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1nik, resolution 4.10Å" /> | caption="1nik, resolution 4.10Å" /> | ||
'''Wild Type RNA Polymerase II'''<br /> | '''Wild Type RNA Polymerase II'''<br /> | ||
==Overview== | ==Overview== | ||
The x-ray structure of complete RNA polymerase II from Saccharomyces | The x-ray structure of complete RNA polymerase II from Saccharomyces cerevisiae has been determined, including a heterodimer of subunits Rpb4 and Rpb7 not present in previous "core" polymerase II structures. The heterodimer maintains the polymerase in the conformation of a transcribing complex, may bind RNA as it emerges from the enzyme, and is in a position to interact with general transcription factors and the Mediator of transcriptional regulation. | ||
==About this Structure== | ==About this Structure== | ||
1NIK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] Full crystallographic information is available from [http:// | 1NIK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NIK OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Bushnell, D | [[Category: Bushnell, D A.]] | ||
[[Category: Kornberg, R | [[Category: Kornberg, R D.]] | ||
[[Category: ZN]] | [[Category: ZN]] | ||
[[Category: transferase]] | [[Category: transferase]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:06:28 2008'' | ||
