1nbb: Difference between revisions

Revision as of 15:04, 21 February 2008

N-BUTYLISOCYANIDE BOUND RHODOBACTER CAPSULATUS CYTOCHROME C'

OverviewOverview

We have determined the structure of n-butylisocyanide-bound Rhodobacter capsulatus cytochrome c'. This is the first example of a ligand-bound structure of a class IIa cytochrome c. Compared with the structure of native cytochrome c', there are significant conformational changes of amino acid residues in the haem vicinity, accompanied by a rearrangement of the hydrogen bonding pattern. The results suggest that rearrangements resulting from ligand binding could drive dimer dissociation in some species and also that the haem propionate may participate in proton transfer.

About this StructureAbout this Structure

1NBB is a Single protein structure of sequence from Rhodobacter capsulatus with and as ligands. Full crystallographic information is available from OCA.

ReferenceReference

Concerted movement of side chains in the haem vicinity observed on ligand binding in cytochrome c' from rhodobacter capsulatus., Tahirov TH, Misaki S, Meyer TE, Cusanovich MA, Higuchi Y, Yasuoka N, Nat Struct Biol. 1996 May;3(5):459-64. PMID:8612077

Page seeded by OCA on Thu Feb 21 14:04:13 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1nbb.gif|left|200px]]<br /><applet load="1nbb" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1nbb.gif|left|200px]]<br /><applet load="1nbb" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1nbb, resolution 2.4&Aring;" />
 '''N-BUTYLISOCYANIDE BOUND RHODOBACTER CAPSULATUS CYTOCHROME C''''<br />
 ==Overview==
-We have determined the structure of n-butylisocyanide-bound Rhodobacter, capsulatus cytochrome c'. This is the first example of a ligand-bound, structure of a class IIa cytochrome c. Compared with the structure of, native cytochrome c', there are significant conformational changes of, amino acid residues in the haem vicinity, accompanied by a rearrangement, of the hydrogen bonding pattern. The results suggest that rearrangements, resulting from ligand binding could drive dimer dissociation in some, species and also that the haem propionate may participate in proton, transfer.
+We have determined the structure of n-butylisocyanide-bound Rhodobacter capsulatus cytochrome c'. This is the first example of a ligand-bound structure of a class IIa cytochrome c. Compared with the structure of native cytochrome c', there are significant conformational changes of amino acid residues in the haem vicinity, accompanied by a rearrangement of the hydrogen bonding pattern. The results suggest that rearrangements resulting from ligand binding could drive dimer dissociation in some species and also that the haem propionate may participate in proton transfer.
 ==About this Structure==
-NBB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus] with HEM and NBN as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NBB OCA].
+NBB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus] with <scene name='pdbligand=HEM:'>HEM</scene> and <scene name='pdbligand=NBN:'>NBN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NBB OCA].
 ==Reference==
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 [[Category: Rhodobacter capsulatus]]
 [[Category: Single protein]]
-[[Category: Cusanovich, M.A.]]
+[[Category: Cusanovich, M A.]]
 [[Category: Higuchi, Y.]]
-[[Category: Meyer, T.E.]]
+[[Category: Meyer, T E.]]
 [[Category: Misaki, S.]]
-[[Category: Tahirov, T.H.]]
+[[Category: Tahirov, T H.]]
 [[Category: Yasuoka, N.]]
 [[Category: HEM]]
@@ Line 25: / Line 25: @@
 [[Category: heme protein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 22:06:50 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:04:13 2008''