2r3q: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[2r3q]] is a 1 chain structure | [[2r3q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3Q OCA]. | ||
==See Also== | ==See Also== |
Revision as of 18:40, 20 October 2012
Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitorCrystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
Template:ABSTRACT PUBMED 17937404
About this StructureAbout this Structure
2r3q is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Fischmann TO, Hruza A, Duca JS, Ramanathan L, Mayhood T, Windsor WT, Le HV, Guzi TJ, Dwyer MP, Paruch K, Doll RJ, Lees E, Parry D, Seghezzi W, Madison V. Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers. 2007 Oct 15;. PMID:17937404 doi:http://dx.doi.org/10.1002/bip.20868
- ↑ Dwyer MP, Paruch K, Alvarez C, Doll RJ, Keertikar K, Duca J, Fischmann TO, Hruza A, Madison V, Lees E, Parry D, Seghezzi W, Sgambellone N, Shanahan F, Wiswell D, Guzi TJ. Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6216-9. Epub 2007 Sep 8. PMID:17904366 doi:http://dx.doi.org/10.1016/j.bmcl.2007.09.018
- ↑ Paruch K, Dwyer MP, Alvarez C, Brown C, Chan TY, Doll RJ, Keertikar K, Knutson C, McKittrick B, Rivera J, Rossman R, Tucker G, Fischmann TO, Hruza A, Madison V, Nomeir AA, Wang Y, Lees E, Parry D, Sgambellone N, Seghezzi W, Schultz L, Shanahan F, Wiswell D, Xu X, Zhou Q, James RA, Paradkar VM, Park H, Rokosz LR, Stauffer TM, Guzi TJ. Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6220-3. Epub 2007 Sep 8. PMID:17904841 doi:10.1016/j.bmcl.2007.09.017