3fcu: Difference between revisions

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{{Seed}}
[[Image:3fcu.png|left|200px]]
[[Image:3fcu.jpg|left|200px]]


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{{STRUCTURE_3fcu|  PDB=3fcu  |  SCENE=  }}  
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===Structure of headpiece of integrin aIIBb3 in open conformation===
===Structure of headpiece of integrin aIIBb3 in open conformation===


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{{ABSTRACT_PUBMED_19111664}}


==Disease==
==About this Structure==
Known disease associated with this structure: Glanzmann thrombasthenia, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]], Thrombocytopenia, neonatal alloimmune OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]]
[[3fcu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FCU OCA].


==About this Structure==
==See Also==
3FCU is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FCU OCA].
*[[Integrin|Integrin]]


==Reference==
==Reference==
<ref group="xtra">PMID:19111664</ref><references group="xtra"/>
<ref group="xtra">PMID:019111664</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Luo, B H.]]
[[Category: Luo, B H.]]
Line 35: Line 23:
[[Category: Zhu, J.]]
[[Category: Zhu, J.]]
[[Category: Allostery]]
[[Category: Allostery]]
[[Category: Alternative splicing]]
[[Category: Cell adhesion]]
[[Category: Cell adhesion]]
[[Category: Cell adhesion/blood clotting complex]]
[[Category: Cell adhesion-blood clotting complex]]
[[Category: Cell adhesion/immune system complex]]
[[Category: Cell adhesion-immune system complex]]
[[Category: Crystal structure]]
[[Category: Crystal structure]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
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[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Platelet integrin alphaiibbeta3]]
[[Category: Platelet integrin alphaiibbeta3]]
[[Category: Polymorphism]]
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Therapeutic antagonism]]
[[Category: Therapeutic antagonism]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 21 10:49:26 2009''

Revision as of 18:27, 20 October 2012

File:3fcu.png

Template:STRUCTURE 3fcu

Structure of headpiece of integrin aIIBb3 in open conformationStructure of headpiece of integrin aIIBb3 in open conformation

Template:ABSTRACT PUBMED 19111664

About this StructureAbout this Structure

3fcu is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol Cell. 2008 Dec 26;32(6):849-61. PMID:19111664 doi:10.1016/j.molcel.2008.11.018

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