1gj4: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[1gj4]] is a 3 chain structure | [[1gj4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GJ4 OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 15:58, 20 October 2012
SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGNSELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN
Template:ABSTRACT PUBMED 11731301
About this StructureAbout this Structure
1gj4 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Katz BA, Sprengeler PA, Luong C, Verner E, Elrod K, Kirtley M, Janc J, Spencer JR, Breitenbucher JG, Hui H, McGee D, Allen D, Martelli A, Mackman RL. Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem Biol. 2001 Nov;8(11):1107-21. PMID:11731301
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Homo sapiens
- Thrombin
- Allen, D.
- Breitenbucher, J G.
- Hui, H.
- Katz, B A.
- Luong, C.
- Mackman, R L.
- Martelli, A.
- McGee, D.
- Spencer, J R.
- Sprengeler, P A.
- Verner, E.
- Blood clotting
- Hydrolase
- Hydrolase-hydrolase inhibitor complex
- Oxyanion hole water
- Shift of pka of his57
- Specificity
- Structure-based drug design
- Three-centered
- Trypsin
- Urokinase
- Very short hydrogen bond
- Zn+2-mediated inhibition