1mwp: Difference between revisions

Revision as of 10:05, 20 October 2012

Structural annotation:
Resources:	CATH : 1Mwpa00 InterPro : Ipr011178, Ipr008155, Ipr008154, Ipr015849, Ipr002223, Ipr013803 Pfam : PF02177 SCOP : d1mwpa_ UniProt : P05067

Functional annotation:
Cellular component:	extracellular region membrane integral to membrane integral to plasma membrane cell surface coated pit
Biological process:	endocytosis apoptosis cellular copper ion homeostasis cell adhesion Notch signaling pathway neuromuscular process
Molecular function:	heparin binding endopeptidase inhibitor activity zinc ion binding protein binding copper ion binding metal ion binding identical protein binding iron ion binding serine-type endopeptidase inhibitor activity binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

1mwp is a 1 chain structure with sequence from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. Full crystallographic information is available from OCA.

↑ Rossjohn J, Cappai R, Feil SC, Henry A, McKinstry WJ, Galatis D, Hesse L, Multhaup G, Beyreuther K, Masters CL, Parker MW. Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat Struct Biol. 1999 Apr;6(4):327-31. PMID:10201399 doi:10.1038/7562
↑ Sandelin E. On hydrophobicity and conformational specificity in proteins. Biophys J. 2004 Jan;86(1 Pt 1):23-30. PMID:14695246 doi:10.1016/S0006-3495(04)74080-1

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 ==About this Structure==
-[[1mwp]] is a 1 chain structure of [[Amyloid precursor protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Amyloid-beta Precursor Protein''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_7 10.2210/rcsb_pdb/mom_2006_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWP OCA].
+[[1mwp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Amyloid-beta Precursor Protein''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_7 10.2210/rcsb_pdb/mom_2006_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWP OCA].
 ==See Also==