Group:MUZIC:CapZ: Difference between revisions
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Cap Z is a heterodimer composed of two subunits <scene name='User:Mara_Camelia_Rusu/Workbench/CapZ/Alpha_subunit/1'>α</scene> and <scene name='User:Mara_Camelia_Rusu/Workbench/CapZ/Beta_subunit/1'>β</scene> and there are at least two isoforms of each of the subunits. In cardiomyocites the β1 containing isoform localizes to the Z-disk and β2 containing isoform localizes to the cell periphery and intercalated disc. | Cap Z is a heterodimer composed of two subunits <scene name='User:Mara_Camelia_Rusu/Workbench/CapZ/Alpha_subunit/1'>α</scene> and <scene name='User:Mara_Camelia_Rusu/Workbench/CapZ/Beta_subunit/1'>β</scene> and there are at least two isoforms of each of the subunits. In cardiomyocites the β1 containing isoform localizes to the Z-disk and β2 containing isoform localizes to the cell periphery and intercalated disc. | ||
The crystal structure of the sarcomeric form has been resolved to a resolution of 2.1 Å by X-ray crystallography (1IZN). <ref>PMID:12660160</ref> | The crystal structure of the sarcomeric form has been resolved to a resolution of 2.1 Å by X-ray crystallography (1IZN). <ref>PMID:12660160</ref> | ||
<Structure load='1IZN' size='500' frame='true' align='right' caption=' | <Structure load='1IZN' size='500' frame='true' align='right' caption='Crystal structure of chicken CapZ expressed in E.coli' scene='Insert optional scene name here' /> | ||
== Structure == | == Structure == | ||