Argonaute: Difference between revisions

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<StructureSection load='4EI1' size='350' side='right' caption='Structure of human Argonaute2 protein in complex with target RNA (PDB Entry [[4EI1]])' scene=''>
The Argonaute family of proteins is central to the RNA-induced silencing in eukaryotic organisms <ref>pmid 22539551</ref>. It was first found to be important for plant development and for germline stem-cell division in ''Drosophila Melanogaster'', but further research revealed a much broader and essential role in protein synthesis, maintenance of genome integrity and RNA stability <ref>pmid 18073770</ref>.
The Argonaute family of proteins is central to the RNA-induced silencing in eukaryotic organisms <ref>pmid 22539551</ref>. It was first found to be important for plant development and for germline stem-cell division in ''Drosophila Melanogaster'', but further research revealed a much broader and essential role in protein synthesis, maintenance of genome integrity and RNA stability <ref>pmid 18073770</ref>.
<StructureSection load='4EI1' size='350' side='right' caption='Structure of human Argonaute2 protein in complex with target RNA (PDB Entry [[4EI1]])' scene=''>
</StructureSection>
</StructureSection>
==The Argonaute Family==
==The Argonaute Family==
===Role in RNA interference===
===Role in RNA interference===

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João Rodrigues, Michal Harel, Joel L. Sussman, Alexander Berchansky