Nuclear receptor: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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 ==== DBD (DNA Binding Domain) ====
 ==== LBD (Ligand Binding Domain) ====
-<StructureSection load='1ie8' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[1ie8]])' scene=''>
+<StructureSection load='1ie8' size='350' side='right' caption='Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry [[1ie8]])' scene=''>
-The LBD of a nuclear receptor has a common three layer sandwich
+The structure of the LBD is strongly conserved throughout the familly of nuclear receptors.
+It is completely folded and composed of a beta-sheet, and 12 alpha-helices arranged in a three layered sandwich.
 </StructureSection>