4flh: Difference between revisions
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[[Image:4flh.jpg|left|200px]] | |||
{{STRUCTURE_4flh| PDB=4flh | SCENE= }} | |||
===Crystal structure of human PI3K-gamma in complex with AMG511=== | |||
{{ABSTRACT_PUBMED_22897589}} | |||
==About this Structure== | |||
[[4flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FLH OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022897589</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Tang, J.]] | |||
[[Category: Whittington, D A.]] | |||
[[Category: Yakowec, P.]] | |||
[[Category: Cancer]] | |||
[[Category: P110]] | |||
[[Category: P85]] | |||
[[Category: Phosphorylation]] | |||
[[Category: Phosphotransferase]] | |||
[[Category: Transferase-inhibitor complex]] | |||
Revision as of 08:14, 29 August 2012
Crystal structure of human PI3K-gamma in complex with AMG511Crystal structure of human PI3K-gamma in complex with AMG511
Template:ABSTRACT PUBMED 22897589
About this StructureAbout this Structure
4flh is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Norman MH, Liu L, Andrews K, Bo Y, Booker S, Caenepeel S, Cee VJ, D'Angelo ND, Freeman DJ, Herberich B, Hong FT, Jackson C, Jiang J, Lannman B, McCarter JD, Mullady E, Nishimura N, Pettus LH, Reed A, San Miguel T, Smith A, Stec MM, Tadesse S, Tasker A, Aidasani D, Zhu S, Subramanian R, Tamayo NA, Wang L, Whittington DA, Wu B, Wu T, Wurz RP, Yang K, Zalameda L, Zhang N, Hughes P. Selective Class I Phosphoinositide 3-Kinase (PI3K) Inhibitors: Optimization of a Series of Pyridyl-triazines Leading to the Identification of a Clinical Candidate, AMG 511. J Med Chem. 2012 Aug 16. PMID:22897589 doi:10.1021/jm300846z