4awq: Difference between revisions

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'''Unreleased structure'''
[[Image:4awq.jpg|left|200px]]


The entry 4awq is ON HOLD until Paper Publication
{{STRUCTURE_4awq|  PDB=4awq  |  SCENE=  }}


Authors: Lougheed, J.C., Stout, T.J.
===Complex of HSP90 ATPase domain with tropane derived inhibitors===


Description: Complex of HSP90 ATPase domain with tropane derived inhibitors
{{ABSTRACT_PUBMED_22877636}}
 
==About this Structure==
[[4awq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AWQ OCA].
 
==Reference==
<ref group="xtra">PMID:022877636</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Non-chaperonin molecular chaperone ATPase]]
[[Category: Lougheed, J C.]]
[[Category: Stout, T J.]]
[[Category: Chaperone]]

Revision as of 08:06, 29 August 2012

File:4awq.jpg

Template:STRUCTURE 4awq

Complex of HSP90 ATPase domain with tropane derived inhibitorsComplex of HSP90 ATPase domain with tropane derived inhibitors

Template:ABSTRACT PUBMED 22877636

About this StructureAbout this Structure

4awq is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Bussenius J, Blazey CM, Aay N, Anand NK, Arcalas A, Baik T, Bowles OJ, Buhr CA, Costanzo S, Curtis JK, Defina SC, Dubenko L, Heuer TS, Huang P, Jaeger C, Joshi A, Kennedy AR, Kim AI, Lara K, Lee J, Li J, Lougheed JC, Ma S, Malek S, Manalo JC, Martini JF, McGrath G, Nicoll M, Nuss JM, Pack M, Peto CJ, Tsang TH, Wang L, Womble SW, Yakes M, Zhang W, Rice KD. Discovery of XL888: A novel tropane-derived small molecule inhibitor of HSP90. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5396-404. Epub 2012 Jul 21. PMID:22877636 doi:10.1016/j.bmcl.2012.07.052

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