G09SecL04Tpc2: Difference between revisions

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Revision as of 11:11, 16 August 2012 view source Nabil Faridi (talk \| contribs) 69 edits No edit summary ← Older edit		Revision as of 11:12, 16 August 2012 view source Nabil Faridi (talk \| contribs) 69 edits No edit summary Newer edit →
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	Upon infection, OspA is immediately downregulated or can even be turned off. Because of this, vaccinations for OspA are virtually ineffective once spirochetes have entered the host. Downregulation also makes OspA harder to detect; OspA is usually upregulated in the late stages of the disease and leads to more serious inflammatory disorders in the central nervous system.		Upon infection, OspA is immediately downregulated or can even be turned off. Because of this, vaccinations for OspA are virtually ineffective once spirochetes have entered the host. Downregulation also makes OspA harder to detect; OspA is usually upregulated in the late stages of the disease and leads to more serious inflammatory disorders in the central nervous system.