G09SecL04Tpc2: Difference between revisions
Nabil Faridi (talk | contribs) No edit summary |
Nabil Faridi (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
[[Image: | [[Image:Ospapic2.gif|thumb|right|Scanning electron micrograph of the spirochete ''Borrelia burgdorferi'', causative agent of Lyme disease.]] | ||
Outer | '''Outer Surface Protein A (OspA)''' is a major [http://en.wikipedia.org/wiki/Lipoprotein lipoprotein] on the [http://en.wikipedia.org/wiki/Borrelia_burgdorferi ''borrelia burgdorferi''] [http://en.wikipedia.org/wiki/Spirochete spirochete] which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions that are associated with [http://en.wikipedia.org/wiki/Lyme_Disease Lyme Disease] such as late stage neurological disorders. | ||
== Outer Surface Protein A (OspA) == | == Outer Surface Protein A (OspA) == | ||
<Structure load='1fj1' size=' | <Structure load='1fj1' size='375' frame='true' align='right' caption='Outer Surface Protein A Fab LA-2 Complex' scene='Insert optional scene name here' /> | ||
== Introduction to Lyme Disease == | == Introduction to Lyme Disease == | ||