OspA L03 Group2: Difference between revisions

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Chris DiFiore, Yimei Miao, Kareema Roushdy, Michal Harel

Revision as of 06:23, 16 August 2012 view source Chris DiFiore (talk \| contribs) 41 edits No edit summary ← Older edit		Revision as of 07:47, 16 August 2012 view source Chris DiFiore (talk \| contribs) 41 edits No edit summary Newer edit →
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	=== LA-2 ===		=== LA-2 ===
	The reactive LA-2 antibody was found to serve as an important epitope of Osp-A binding <ref name=Ding >PMID: 11183781</ref> towards developing vaccinations. The protein, OspA obtained from PDB was dissected to isolate and concentrate the F chain from the molecule of OspA from the crystallized structure to show the free state of the 3D model exposing the C-terminal to express the interaction with the Fab antigen combing site exposing the 3-loops and 49 residues involved where LA-2 makes direct contact <ref name=Ding >PMID: 11183781</ref>. Studies were shown through findings from nuclear magnetic resonance, or [http://en.wikipedia.org/wiki/Nuclear_magnetic_resonance NMR] and [http://en.wikipedia.org/wiki/Protein_crystallization crystallization] <ref name=Ding >PMID: 11183781</ref>.		The reactive <scene name='OspA_L03_Group2/La-2/2'>LA-2 antibody</scene> was found to serve as an important epitope of Osp-A binding <ref name=Ding >PMID: 11183781</ref> towards developing vaccinations. The protein, OspA obtained from PDB was dissected to isolate and concentrate the F chain from the molecule of OspA from the crystallized structure to show the free state of the 3D model exposing the C-terminal to express the interaction with the Fab antigen combing site exposing the 3-loops and 49 residues involved where LA-2 makes direct contact <ref name=Ding >PMID: 11183781</ref>. Studies were shown through findings from nuclear magnetic resonance, or [http://en.wikipedia.org/wiki/Nuclear_magnetic_resonance NMR] and [http://en.wikipedia.org/wiki/Protein_crystallization crystallization] <ref name=Ding >PMID: 11183781</ref>.