2g3v: Difference between revisions

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[[Image:2g3v.gif|left|200px]]
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{{STRUCTURE_2g3v|  PDB=2g3v  |  SCENE=  }}  
{{STRUCTURE_2g3v|  PDB=2g3v  |  SCENE=  }}  


'''Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori'''
===Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori===


 
{{ABSTRACT_PUBMED_15223328}}
==Overview==
CagZ, a 23 kDa protein encoded by the cagZ gene (HP0526) of the cag pathogenicity island of Helicobacter pylori, has been cloned, over-expressed, purified and its three-dimensional structure determined. The protein consists of a single compact L-shaped domain, composed of seven alpha-helices including about 70% of the total residues. Three-dimensional homology searches did not reveal structural homologues, and CagZ can be considered representative of a new protein fold. The presence of a disordered C-terminal tail and the nature of the molecular surface suggest that CagZ may participate in the interaction of effector proteins with one or more components of the H.pylori type IV secretion system on the cytoplasmic side of the inner membrane.


==About this Structure==
==About this Structure==
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3V OCA].  
[[2g3v]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3V OCA].  


==Reference==
==Reference==
Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system., Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G, J Mol Biol. 2004 Jul 16;340(4):881-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15223328 15223328]
<ref group="xtra">PMID:015223328</ref><ref group="xtra">PMID:017623849</ref><references group="xtra"/>
[[Category: Helicobacter pylori]]
[[Category: Angelini, A.]]
[[Category: Angelini, A.]]
[[Category: Battistutta, R.]]
[[Category: Battistutta, R.]]
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[[Category: Pathogenicity island]]
[[Category: Pathogenicity island]]
[[Category: Type iv secretion system]]
[[Category: Type iv secretion system]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 04:39:39 2008''
[[Category: Unknown function]]

Revision as of 21:19, 14 August 2012

File:2g3v.png

Template:STRUCTURE 2g3v

Crystal structure of CagS (HP0534, Cag13) from Helicobacter pyloriCrystal structure of CagS (HP0534, Cag13) from Helicobacter pylori

Template:ABSTRACT PUBMED 15223328

About this StructureAbout this Structure

2g3v is a 8 chain structure with sequence from Helicobacter pylori. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G. Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system. J Mol Biol. 2004 Jul 16;340(4):881-9. PMID:15223328 doi:10.1016/j.jmb.2004.05.016
  2. ↑ Cendron L, Tasca E, Seraglio T, Seydel A, Angelini A, Battistutta R, Montecucco C, Zanotti G. The crystal structure of CagS from the Helicobacter pylori pathogenicity island. Proteins. 2007 Nov 1;69(2):440-3. PMID:17623849 doi:10.1002/prot.21576

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