OspA L03 Group2: Difference between revisions
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=='''Structure'''== | =='''Structure'''== | ||
<Structure load='1FJ1' size='400' align=' | <Structure load='1FJ1' size='400' align='left' caption='Structure of OspA (PDB entry[[1FJ1]])'scene="/> | ||
The model presented by the Protein Data Bank is OspA containing two light chains or Hybridoma Antibody LA2 (chains A and C), two heavy chains or Hyrbridoma Antibody LA2 (chains B and D), and two outer surface protein A (chains E and F). In addition, the original PDB image suggests that the C-terminal domain was unchanged by the LA-2 binding, other than minor shifts in the conformations of all 3-loops to accommodate interactions with the Fab <ref name=Ding >PMID: 11183781</ref>. | The model presented by the Protein Data Bank is OspA containing two light chains or Hybridoma Antibody LA2 (chains A and C), two heavy chains or Hyrbridoma Antibody LA2 (chains B and D), and two outer surface protein A (chains E and F). In addition, the original PDB image suggests that the C-terminal domain was unchanged by the LA-2 binding, other than minor shifts in the conformations of all 3-loops to accommodate interactions with the Fab <ref name=Ding >PMID: 11183781</ref>. | ||