Matrix metalloproteinase: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 32: | Line 32: | ||
'''Matrix metalloproteinases''' (MMP) are Zinc-dependent endopeptidases. MMP degrades extracellular matrix proteins. MMPs are produced by 28 different genes and are classified according to their protein substrates. They are inhibited by proteases called tissue inhibitors of metalloproteinase (TIMP). The pro-MMP contains a pro-peptide which must be removed to render the MMP active. The images at the left and at the right correspond to one representative MMP, ''i.e.'' the crystal structure of human pro MMP1 ([[1su3]]). See details of MMP12 in [[Matrix Metalloproteinase 12]]. More details of MMP in [[Matrix metalloproteinases]] | '''Matrix metalloproteinases''' (MMP) are Zinc-dependent endopeptidases. MMP degrades extracellular matrix proteins. MMPs are produced by 28 different genes and are classified according to their protein substrates. They are inhibited by proteases called tissue inhibitors of metalloproteinase (TIMP). The pro-MMP contains a pro-peptide which must be removed to render the MMP active. The images at the left and at the right correspond to one representative MMP, ''i.e.'' the crystal structure of human pro MMP1 ([[1su3]]). See details of MMP12 in [[Matrix Metalloproteinase 12]]. More details of MMP in | ||
* [[Matrix metalloproteinases]] | |||
* [[Metalloproteases]] | |||
* [[MT1-MMP-TIMP-1 complex]]. | |||
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||