1vz5: Difference between revisions
New page: left|200px<br /> <applet load="1vz5" size="450" color="white" frame="true" align="right" spinBox="true" caption="1vz5, resolution 2.15Å" /> '''SUCCINATE COMPLEX O... |
No edit summary |
||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
1VZ5 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]] with SIN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1VZ5 OCA]]. | 1VZ5 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]] with SIN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1VZ5 OCA]]. | ||
==Reference== | ==Reference== | ||
| Line 26: | Line 26: | ||
[[Category: sulfatase]] | [[Category: sulfatase]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:15:16 2007'' | ||
Revision as of 15:10, 30 October 2007
|
SUCCINATE COMPLEX OF ATSK
OverviewOverview
The alkylsulfatase AtsK from Pseudomonas putida S-313 is a member of the, non-heme iron(II)-alpha-ketoglutarate-dependent dioxygenase superfamily., In the initial step of their catalytic cycle, enzymes belonging to this, widespread and versatile family coordinate molecular oxygen to the iron, center in the active site. The subsequent decarboxylation of the, cosubstrate alpha-ketoglutarate yields carbon dioxide, succinate, and a, highly reactive ferryl (IV) species, which is required for substrate, oxidation via a complex mechanism involving the transfer of radical, species. Non-productive activation of oxygen may lead to harmful side, reactions; therefore, such enzymes need an effective built-in protection, mechanism. One of the ways of controlling undesired side reactions is the, ... [(full description)]
About this StructureAbout this Structure
1VZ5 is a [Single protein] structure of sequence from [Pseudomonas putida] with SIN as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
ReferenceReference
Succinate complex crystal structures of the alpha-ketoglutarate-dependent dioxygenase AtsK: steric aspects of enzyme self-hydroxylation., Muller I, Stuckl C, Wakeley J, Kertesz M, Uson I, J Biol Chem. 2005 Feb 18;280(7):5716-23. Epub 2004 Nov 12. PMID:15542595
Page seeded by OCA on Tue Oct 30 14:15:16 2007