2fir: Difference between revisions

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{{Seed}}
[[Image:2fir.png|left|200px]]
[[Image:2fir.png|left|200px]]


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===Crystal structure of DFPR-VIIa/sTF===
===Crystal structure of DFPR-VIIa/sTF===


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{{ABSTRACT_PUBMED_16757484}}
{{ABSTRACT_PUBMED_16757484}}


==Disease==
==About this Structure==
Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]]
[[2fir]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIR OCA].


==About this Structure==
==See Also==
2FIR is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIR OCA].
*[[Factor VIIa|Factor VIIa]]


==Reference==
==Reference==
<ref group="xtra">PMID:16757484</ref><references group="xtra"/>
<ref group="xtra">PMID:016757484</ref><references group="xtra"/>
[[Category: Coagulation factor VIIa]]
[[Category: Coagulation factor VIIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 35: Line 23:
[[Category: Schmidt, A E.]]
[[Category: Schmidt, A E.]]
[[Category: Schreuder, H.]]
[[Category: Schreuder, H.]]
[[Category: Blood clotting]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Factor viia]]
[[Category: Factor viia]]
[[Category: Magnesium]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Oxyanion hole]]
[[Category: Oxyanion hole]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Sodium]]
[[Category: Soluble tissue factor]]
[[Category: Soluble tissue factor]]
[[Category: Zinc]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:43:37 2009''

Revision as of 16:15, 27 July 2012

File:2fir.png


PDB ID 2fir

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2fir, resolution 2.00Å ()
Ligands: , , , , , , ,
Non-Standard Residues:
Gene: F7 (Homo sapiens), F3 (Homo sapiens)
Activity: Coagulation factor VIIa, with EC number 3.4.21.21
Related: 1dan, 2a2q, 2aer, 2b8o
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Crystal structure of DFPR-VIIa/sTFCrystal structure of DFPR-VIIa/sTF

Template:ABSTRACT PUBMED 16757484

About this StructureAbout this Structure

2fir is a 3 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J Biol Chem. 2006 Aug 25;281(34):24873-88. Epub 2006 Jun 6. PMID:16757484 doi:10.1074/jbc.M509971200

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