3sh2: Difference between revisions

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[[Image:3sh2.jpg|left|200px]]
[[Image:3sh2.png|left|200px]]


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===Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)===
===Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)===


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{{ABSTRACT_PUBMED_22347365}}
{{ABSTRACT_PUBMED_22347365}}


==About this Structure==
==About this Structure==
[[3sh2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SH2 OCA].  
[[3sh2]] is a 2 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SH2 OCA].  
 
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]


==Reference==
==Reference==

Revision as of 15:45, 27 July 2012

File:3sh2.png

Template:STRUCTURE 3sh2

Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)

Template:ABSTRACT PUBMED 22347365

About this StructureAbout this Structure

3sh2 is a 2 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Viswanathan K, Frey KM, Scocchera EW, Martin BD, Swain Iii PW, Alverson JB, Priestley ND, Anderson AC, Wright DL. Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes. PLoS One. 2012;7(2):e29434. Epub 2012 Feb 7. PMID:22347365 doi:10.1371/journal.pone.0029434

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