3sh2: Difference between revisions
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[[Image:3sh2. | [[Image:3sh2.png|left|200px]] | ||
{{STRUCTURE_3sh2| PDB=3sh2 | SCENE= }} | {{STRUCTURE_3sh2| PDB=3sh2 | SCENE= }} | ||
===Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)=== | ===Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)=== | ||
{{ABSTRACT_PUBMED_22347365}} | {{ABSTRACT_PUBMED_22347365}} | ||
==About this Structure== | ==About this Structure== | ||
[[3sh2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SH2 OCA]. | [[3sh2]] is a 2 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SH2 OCA]. | ||
==See Also== | |||
*[[Dihydrofolate reductase|Dihydrofolate reductase]] | |||
==Reference== | ==Reference== |
Revision as of 15:45, 27 July 2012
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)
Template:ABSTRACT PUBMED 22347365
About this StructureAbout this Structure
3sh2 is a 2 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Viswanathan K, Frey KM, Scocchera EW, Martin BD, Swain Iii PW, Alverson JB, Priestley ND, Anderson AC, Wright DL. Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes. PLoS One. 2012;7(2):e29434. Epub 2012 Feb 7. PMID:22347365 doi:10.1371/journal.pone.0029434