1c1v: Difference between revisions

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[[Image:1c1v.png|left|200px]]
[[Image:1c1v.png|left|200px]]


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{{STRUCTURE_1c1v|  PDB=1c1v  |  SCENE=  }}  
{{STRUCTURE_1c1v|  PDB=1c1v  |  SCENE=  }}  


===RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES===
===RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES===


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{{ABSTRACT_PUBMED_9468142}}
{{ABSTRACT_PUBMED_9468142}}


==About this Structure==
==About this Structure==
[[1c1v]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C1V OCA].  
[[1c1v]] is a 3 chain structure of [[Cytochrome c peroxidase]], [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C1V OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Cytochrome c peroxidase|Cytochrome c peroxidase]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:9468142</ref><references group="xtra"/>
<ref group="xtra">PMID:009468142</ref><references group="xtra"/>
[[Category: Hirudo medicinalis]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Luong, C.]]
[[Category: Luong, C.]]
[[Category: Blood clotting]]
[[Category: Blood clotting]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Ph dependence]]
[[Category: Ph dependence]]
[[Category: Serine protease/inhibitor]]
[[Category: Serine protease/inhibitor]]

Revision as of 15:04, 27 July 2012

File:1c1v.png

Template:STRUCTURE 1c1v

RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASESRECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES

Template:ABSTRACT PUBMED 9468142

About this StructureAbout this Structure

1c1v is a 3 chain structure of Cytochrome c peroxidase, Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Katz BA, Clark JM, Finer-Moore JS, Jenkins TE, Johnson CR, Ross MJ, Luong C, Moore WR, Stroud RM. Design of potent selective zinc-mediated serine protease inhibitors. Nature. 1998 Feb 5;391(6667):608-12. PMID:9468142 doi:http://dx.doi.org/10.1038/35422

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