2f54: Difference between revisions

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{{Seed}}
[[Image:2f54.png|left|200px]]
[[Image:2f54.png|left|200px]]


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===Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity===
===Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity===


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{{ABSTRACT_PUBMED_16600963}}
{{ABSTRACT_PUBMED_16600963}}


==Disease==
==About this Structure==
Known disease associated with this structure: Hypoproteinemia, hypercatabolic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=109700 109700]]
[[2f54]] is a 10 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F54 OCA].


==About this Structure==
==See Also==
2F54 is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F54 OCA].
*[[Beta-2 microglobulin|Beta-2 microglobulin]]
*[[Major histocompatibility complex|Major histocompatibility complex]]


==Reference==
==Reference==
<ref group="xtra">PMID:16600963</ref><references group="xtra"/>
<ref group="xtra">PMID:016600963</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Dunn, S M.]]
[[Category: Dunn, S M.]]
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[[Category: Cdr2]]
[[Category: Cdr2]]
[[Category: High affinity]]
[[Category: High affinity]]
[[Category: Immune system]]
[[Category: Ny-eso-1]]
[[Category: Ny-eso-1]]
[[Category: Phage display]]
[[Category: Phage display]]
[[Category: T-cell receptor]]
[[Category: T-cell receptor]]
[[Category: Wild type sequence]]
[[Category: Wild type sequence]]
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