3qk0: Difference between revisions

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[[Image:3qk0.jpg|left|200px]]
[[Image:3qk0.png|left|200px]]


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{{STRUCTURE_3qk0|  PDB=3qk0  |  SCENE=  }}  
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===Crystal structure of PI3K-gamma in complex with benzothiazole 82===
===Crystal structure of PI3K-gamma in complex with benzothiazole 82===


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{{ABSTRACT_PUBMED_21332118}}
{{ABSTRACT_PUBMED_21332118}}


==About this Structure==
==About this Structure==
[[3qk0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QK0 OCA].  
[[3qk0]] is a 1 chain structure of [[Phosphoinositide 3-Kinases]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QK0 OCA].  
 
==See Also==
*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]]


==Reference==
==Reference==
<ref group="xtra">PMID:21332118</ref><references group="xtra"/>
<ref group="xtra">PMID:021332118</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Whittington, D A.]]
[[Category: Whittington, D A.]]
[[Category: Yakowec, P.]]
[[Category: Yakowec, P.]]
[[Category: Atp-binding]]
[[Category: Inhibitor]]
[[Category: Kinase]]
[[Category: P101]]
[[Category: P110]]
[[Category: P84]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 13:15, 27 July 2012

File:3qk0.png

Template:STRUCTURE 3qk0

Crystal structure of PI3K-gamma in complex with benzothiazole 82Crystal structure of PI3K-gamma in complex with benzothiazole 82

Template:ABSTRACT PUBMED 21332118

About this StructureAbout this Structure

3qk0 is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ D'Angelo ND, Kim TS, Andrews K, Booker SK, Caenepeel S, Chen K, D'Amico D, Freeman D, Jiang J, Liu L, McCarter JD, San Miguel T, Mullady EL, Schrag M, Subramanian R, Tang J, Wahl RC, Wang L, Whittington DA, Wu T, Xi N, Xu Y, Yakowec P, Yang K, Zalameda LP, Zhang N, Hughes P, Norman MH. Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors. J Med Chem. 2011 Mar 24;54(6):1789-811. Epub 2011 Feb 18. PMID:21332118 doi:10.1021/jm1014605

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