3gi2: Difference between revisions
Jump to navigation
Jump to search
m Protected "3gi2" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:3gi2.png|left|200px]] | [[Image:3gi2.png|left|200px]] | ||
{{STRUCTURE_3gi2| PDB=3gi2 | SCENE= }} | {{STRUCTURE_3gi2| PDB=3gi2 | SCENE= }} | ||
===Human dihydrofolate reductase Q35K mutant inhibitor complex=== | ===Human dihydrofolate reductase Q35K mutant inhibitor complex=== | ||
{{ABSTRACT_PUBMED_19719239}} | {{ABSTRACT_PUBMED_19719239}} | ||
| Line 22: | Line 11: | ||
==See Also== | ==See Also== | ||
*[[Dihydrofolate reductase]] | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019719239</ref><references group="xtra"/> | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 13:03, 27 July 2012
Human dihydrofolate reductase Q35K mutant inhibitor complexHuman dihydrofolate reductase Q35K mutant inhibitor complex
Template:ABSTRACT PUBMED 19719239
About this StructureAbout this Structure
3gi2 is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Gangjee A, Li W, Kisliuk RL, Cody V, Pace J, Piraino J, Makin J. Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents. J Med Chem. 2009 Aug 13;52(15):4892-902. PMID:19719239 doi:10.1021/jm900490a