2v2h: Difference between revisions

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[[Image:2v2h.png|left|200px]]
[[Image:2v2h.png|left|200px]]


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===THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM===
===THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM===


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{{ABSTRACT_PUBMED_18219118}}
{{ABSTRACT_PUBMED_18219118}}


==About this Structure==
==About this Structure==
2V2H is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2H OCA].  
[[2v2h]] is a 3 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2H OCA].  
 
==See Also==
*[[TIM test|TIM test]]
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18219118</ref><references group="xtra"/>
<ref group="xtra">PMID:018219118</ref><references group="xtra"/>
[[Category: Triose-phosphate isomerase]]
[[Category: Triose-phosphate isomerase]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Trypanosoma brucei brucei]]
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[[Category: Tim-barrel]]
[[Category: Tim-barrel]]
[[Category: Triosephosphate isomerase]]
[[Category: Triosephosphate isomerase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:41:44 2009''

Revision as of 12:56, 27 July 2012

File:2v2h.png

Template:STRUCTURE 2v2h

THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIMTHE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM

Template:ABSTRACT PUBMED 18219118

About this StructureAbout this Structure

2v2h is a 3 chain structure of TIM test and Triose Phosphate Isomerase with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Alahuhta M, Casteleijn MG, Neubauer P, Wierenga RK. Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM. Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):178-88. Epub 2008, Jan 16. PMID:18219118 doi:10.1107/S0907444907059021

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