2j7a: Difference between revisions
New page: left|200px<br /> <applet load="2j7a" size="450" color="white" frame="true" align="right" spinBox="true" caption="2j7a, resolution 2.30Å" /> '''CRYSTAL STRUCTURE O... |
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==About this Structure== | ==About this Structure== | ||
2J7A is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]] with CA, ACT, HEM and LMT as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J7A OCA]]. | 2J7A is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]] with CA, ACT, HEM and LMT as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J7A OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: quinol dehydrogenase]] | [[Category: quinol dehydrogenase]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:09:48 2007'' | ||
Revision as of 15:05, 30 October 2007
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CRYSTAL STRUCTURE OF CYTOCHROME C NITRITE REDUCTASE NRFHA COMPLEX FROM DESULFOVIBRIO VULGARIS
OverviewOverview
Oxidation of membrane-bound quinol molecules is a central step in the, respiratory electron transport chains used by biological cells to generate, ATP by oxidative phosphorylation. A novel family of cytochrome c quinol, dehydrogenases that play an important role in bacterial respiratory chains, was recognised in recent years. Here, we describe the first structure of a, cytochrome from this family, NrfH from Desulfovibrio vulgaris, which forms, a stable complex with its electron partner, the cytochrome c nitrite, reductase NrfA. One NrfH molecule interacts with one NrfA dimer in an, asymmetrical manner, forming a large membrane-bound complex with an, overall alpha(4)beta(2) quaternary arrangement. The menaquinol-interacting, NrfH haem is pentacoordinated, bound by a methionine from the ... [(full description)]
About this StructureAbout this Structure
2J7A is a [Protein complex] structure of sequences from [Desulfovibrio vulgaris] with CA, ACT, HEM and LMT as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
ReferenceReference
X-ray structure of the membrane-bound cytochrome c quinol dehydrogenase NrfH reveals novel haem coordination., Rodrigues ML, Oliveira TF, Pereira IA, Archer M, EMBO J. 2006 Dec 13;25(24):5951-60. Epub 2006 Nov 30. PMID:17139260
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