1nce: Difference between revisions

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[[Image:1nce.png|left|200px]]
[[Image:1nce.png|left|200px]]


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===Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717===
===Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717===


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{{ABSTRACT_PUBMED_12702803}}


==About this Structure==
==About this Structure==
1NCE is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli,_and_escherichia_coli_o157:h7 Escherichia coli, and escherichia coli o157:h7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCE OCA].  
[[1nce]] is a 2 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli,_escherichia_coli_o157:h7 Escherichia coli, escherichia coli o157:h7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCE OCA].  
 
==See Also==
*[[Thymidylate synthase|Thymidylate synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:12702803</ref><references group="xtra"/>
<ref group="xtra">PMID:012702803</ref><references group="xtra"/>
[[Category: Escherichia coli, and escherichia coli o157:h7]]
[[Category: Escherichia coli, escherichia coli o157:h7]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
[[Category: Birdsall, D L.]]
[[Category: Birdsall, D L.]]
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[[Category: Asymmetric dimer]]
[[Category: Asymmetric dimer]]
[[Category: Beta-sheet interface]]
[[Category: Beta-sheet interface]]
[[Category: Biosynthetic protein]]
[[Category: Protein-dump-cofactor analog complex]]
[[Category: Protein-dump-cofactor analog complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:44:15 2009''

Revision as of 11:05, 27 July 2012

File:1nce.png

Template:STRUCTURE 1nce

Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717

Template:ABSTRACT PUBMED 12702803

About this StructureAbout this Structure

1nce is a 2 chain structure of Thymidylate synthase with sequence from Escherichia coli, escherichia coli o157:h7. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Birdsall DL, Finer-Moore J, Stroud RM. The only active mutant of thymidylate synthase D169, a residue far from the site of methyl transfer, demonstrates the exquisite nature of enzyme specificity. Protein Eng. 2003 Mar;16(3):229-40. PMID:12702803

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