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Revision as of 10:34, 27 July 2012
Bace1 with the aminohydantoin Compound 37Bace1 with the aminohydantoin Compound 37
Template:ABSTRACT PUBMED 19968289
About this StructureAbout this Structure
3inf is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Malamas MS, Erdei J, Gunawan I, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Jacobsen S, Magolda RL, Pangalos M, Robichaud AJ. Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors. J Med Chem. 2010 Feb 11;53(3):1146-58. PMID:19968289 doi:10.1021/jm901414e