1mue: Difference between revisions

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m Protected "1mue" [edit=sysop:move=sysop]
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[[Image:1mue.png|left|200px]]
[[Image:1mue.png|left|200px]]


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{{STRUCTURE_1mue|  PDB=1mue  |  SCENE=  }}  
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===Thrombin-Hirugen-L405,426===
===Thrombin-Hirugen-L405,426===


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{{ABSTRACT_PUBMED_12657281}}
{{ABSTRACT_PUBMED_12657281}}


==About this Structure==
==About this Structure==
[[1mue]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUE OCA].  
[[1mue]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUE OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:12657281</ref><references group="xtra"/>
<ref group="xtra">PMID:012657281</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Yan, Y.]]
[[Category: Yan, Y.]]
[[Category: Alpha thrombin-hirugen]]
[[Category: Alpha thrombin-hirugen]]
[[Category: Hydrolase/blood clotting complex]]
[[Category: Blood clotting complex]]
[[Category: Hydrolase inhibitor]]
[[Category: Hydrolase inhibitor complex]]

Revision as of 09:33, 27 July 2012

File:1mue.png

Template:STRUCTURE 1mue

Thrombin-Hirugen-L405,426Thrombin-Hirugen-L405,426

Template:ABSTRACT PUBMED 12657281

About this StructureAbout this Structure

1mue is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Burgey CS, Robinson KA, Lyle TA, Nantermet PG, Selnick HG, Isaacs RC, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Stranieri MT, Cook JJ, McMasters DR, Pellicore JM, Pal S, Wallace AA, Clayton FC, Bohn D, Welsh DC, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP. Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. Implementation of P3 pyridine N-oxides to deliver an orally bioavailable series containing P1 N-benzylamides. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1353-7. PMID:12657281

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