1mu8: Difference between revisions

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m Protected "1mu8" [edit=sysop:move=sysop]
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[[Image:1mu8.png|left|200px]]
[[Image:1mu8.png|left|200px]]


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{{STRUCTURE_1mu8|  PDB=1mu8  |  SCENE=  }}  
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===thrombin-hirugen_l-378,650===
===thrombin-hirugen_l-378,650===


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{{ABSTRACT_PUBMED_12570369}}
{{ABSTRACT_PUBMED_12570369}}


==About this Structure==
==About this Structure==
[[1mu8]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MU8 OCA].  
[[1mu8]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MU8 OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:12570369</ref><references group="xtra"/>
<ref group="xtra">PMID:012570369</ref><references group="xtra"/>
[[Category: Hirudo medicinalis]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Wong, B.]]
[[Category: Wong, B.]]
[[Category: Yan, Y.]]
[[Category: Yan, Y.]]
[[Category: Hydrolase/blood clotting complex]]
[[Category: Blood clotting]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Thrombin-hirugen]]
[[Category: Thrombin-hirugen]]

Revision as of 09:28, 27 July 2012

File:1mu8.png

Template:STRUCTURE 1mu8

thrombin-hirugen_l-378,650thrombin-hirugen_l-378,650

Template:ABSTRACT PUBMED 12570369

About this StructureAbout this Structure

1mu8 is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Burgey CS, Robinson KA, Lyle TA, Sanderson PE, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Williams PD, Coburn CA, Dorsey BD, Barrow JC, Stranieri MT, Holahan MA, Sitko GR, Cook JJ, McMasters DR, McDonough CM, Sanders WM, Wallace AA, Clayton FC, Bohn D, Leonard YM, Detwiler TJ Jr, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP. Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines. J Med Chem. 2003 Feb 13;46(4):461-73. PMID:12570369 doi:http://dx.doi.org/10.1021/jm020311f

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