3c1k: Difference between revisions

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[[Image:3c1k.png|left|200px]]
[[Image:3c1k.png|left|200px]]


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{{STRUCTURE_3c1k|  PDB=3c1k  |  SCENE=  }}  
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===Crystal structure of thrombin in complex with inhibitor 15===
===Crystal structure of thrombin in complex with inhibitor 15===


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{{ABSTRACT_PUBMED_18291642}}
{{ABSTRACT_PUBMED_18291642}}


==About this Structure==
==About this Structure==
[[3c1k]] is a 2 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C1K OCA].  
[[3c1k]] is a 2 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C1K OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:18291642</ref><references group="xtra"/>
<ref group="xtra">PMID:018291642</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Acute phase]]
[[Category: Acute phase]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
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[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Kringle]]
[[Category: Kringle]]
[[Category: Pharmaceutical]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Protease inhibitor]]
[[Category: Protease inhibitor]]

Revision as of 07:58, 27 July 2012

File:3c1k.png

Template:STRUCTURE 3c1k

Crystal structure of thrombin in complex with inhibitor 15Crystal structure of thrombin in complex with inhibitor 15

Template:ABSTRACT PUBMED 18291642

About this StructureAbout this Structure

3c1k is a 2 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Isaacs RC, Solinsky MG, Cutrona KJ, Newton CL, Naylor-Olsen AM, McMasters DR, Krueger JA, Lewis SD, Lucas BJ, Kuo LC, Yan Y, Lynch JJ, Lyle EA. Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 2: N-acetamidoimidazoles. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2062-6. Epub 2008 Jan 30. PMID:18291642 doi:10.1016/j.bmcl.2008.01.098

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