2jmn: Difference between revisions

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[[Image:2jmn.png|left|200px]]
[[Image:2jmn.png|left|200px]]


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===NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures===
===NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures===


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==Disease==
==About this Structure==
Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], Hyperproinsulinemia, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], MODY, one form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]]
[[2jmn]] is a 2 chain structure of [[Molecular Playground/Insulin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries  and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vks 1vks]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMN OCA].


==About this Structure==
==See Also==
2JMN is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries  and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vks 1vks]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMN OCA].
*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]


==Reference==
==Reference==
<ref group="xtra">PMID:8951384</ref><references group="xtra"/>
<ref group="xtra">PMID:008951384</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Burke, G T.]]
[[Category: Burke, G T.]]
Line 38: Line 26:
[[Category: Weiss, M A.]]
[[Category: Weiss, M A.]]
[[Category: Hormone]]
[[Category: Hormone]]
[[Category: Hormone-growth factor complex]]
[[Category: Human insulin]]
[[Category: Human insulin]]
[[Category: Mutant]]
[[Category: Mutant]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:52:39 2009''

Revision as of 07:22, 27 July 2012

File:2jmn.png

Template:STRUCTURE 2jmn

NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structuresNMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures

Template:ABSTRACT PUBMED 8951384

About this StructureAbout this Structure

2jmn is a 2 chain structure of Molecular Playground/Insulin with sequence from Homo sapiens. This structure supersedes the now removed PDB entries and 1vks. Full experimental information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Hua QX, Hu SQ, Frank BH, Jia W, Chu YC, Wang SH, Burke GT, Katsoyannis PG, Weiss MA. Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J Mol Biol. 1996 Nov 29;264(2):390-403. PMID:8951384 doi:10.1006/jmbi.1996.0648

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