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1o5c: Difference between revisions

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{{Seed}}
[[Image:1o5c.png|left|200px]]
[[Image:1o5c.png|left|200px]]


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{{STRUCTURE_1o5c|  PDB=1o5c  |  SCENE=  }}  
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===Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)===
===Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)===


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{{ABSTRACT_PUBMED_15522303}}
{{ABSTRACT_PUBMED_15522303}}


==Disease==
==About this Structure==
Known disease associated with this structure: Alzheimer disease, late-onset, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191840 191840]]
[[1o5c]] is a 2 chain structure of [[Urokinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O5C OCA].


==About this Structure==
==See Also==
1O5C is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O5C OCA].
*[[Urokinase|Urokinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15522303</ref><references group="xtra"/>
<ref group="xtra">PMID:015522303</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: U-plasminogen activator]]
[[Category: U-plasminogen activator]]
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[[Category: Young, W B.]]
[[Category: Young, W B.]]
[[Category: Ala190 upa]]
[[Category: Ala190 upa]]
[[Category: Blood clotting]]
[[Category: Conserved water displacement hydrogen bond deficit]]
[[Category: Conserved water displacement hydrogen bond deficit]]
[[Category: Factor viia]]
[[Category: Factor viia]]
[[Category: Hepsin]]
[[Category: Hepsin]]
[[Category: Hydrolase]]
[[Category: S1 site]]
[[Category: S1 site]]
[[Category: Selectivity]]
[[Category: Selectivity]]
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Trypsin]]
[[Category: Trypsin]]
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