2vtr: Difference between revisions
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[[Image:2vtr.png|left|200px]] | [[Image:2vtr.png|left|200px]] | ||
{{STRUCTURE_2vtr| PDB=2vtr | SCENE= }} | {{STRUCTURE_2vtr| PDB=2vtr | SCENE= }} | ||
===IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.=== | ===IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.=== | ||
{{ABSTRACT_PUBMED_18656911}} | {{ABSTRACT_PUBMED_18656911}} | ||
==About this Structure== | ==About this Structure== | ||
[[2vtr]] is a 1 chain structure of [[Cell Division Protein Kinase 2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VTR OCA]. | |||
==See Also== | |||
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018656911</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Berdini, V.]] | [[Category: Berdini, V.]] | ||
| Line 53: | Line 44: | ||
[[Category: Serine/threonine protein kinase]] | [[Category: Serine/threonine protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 06:20, 27 July 2012
IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.
Template:ABSTRACT PUBMED 18656911
About this StructureAbout this Structure
2vtr is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Wyatt PG, Woodhead AJ, Berdini V, Boulstridge JA, Carr MG, Cross DM, Davis DJ, Devine LA, Early TR, Feltell RE, Lewis EJ, McMenamin RL, Navarro EF, O'Brien MA, O'Reilly M, Reule M, Saxty G, Seavers LC, Smith DM, Squires MS, Trewartha G, Walker MT, Woolford AJ. Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design. J Med Chem. 2008 Aug 28;51(16):4986-99. Epub 2008 Jul 26. PMID:18656911 doi:10.1021/jm800382h
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Homo sapiens
- Berdini, V.
- Boulstridge, J A.
- Brien, M A.O.
- Carr, M G.
- Cross, D M.
- Danillon, D.
- Davis, D J.
- Devine, L A.
- Early, T R.
- Feltell, R E.
- Lewis, E J.
- Mcmenamin, R L.
- Navarro, E F.
- Reilly, M O.
- Reule, M.
- Saxty, G.
- Seavers, L C.A.
- Smith, D.
- Squires, M S.
- Trewartha, G.
- Walker, M T.
- Woodhead, A J.
- Woolford, A J.
- Wyatt, P G.
- Cell cycle
- Mitosis
- Serine/threonine protein kinase
- Transferase