3rik: Difference between revisions
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[[Image:3rik. | [[Image:3rik.png|left|200px]] | ||
{{STRUCTURE_3rik| PDB=3rik | SCENE= }} | {{STRUCTURE_3rik| PDB=3rik | SCENE= }} | ||
===The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease=== | ===The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease=== | ||
{{ABSTRACT_PUBMED_22047104}} | {{ABSTRACT_PUBMED_22047104}} | ||
==About this Structure== | ==About this Structure== | ||
[[3rik]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIK OCA]. | [[3rik]] is a 4 chain structure of [[Acid-beta-glucosidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIK OCA]. | ||
==See Also== | |||
*[[Acid-beta-glucosidase|Acid-beta-glucosidase]] | |||
==Reference== | ==Reference== |
Revision as of 03:38, 27 July 2012
The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher diseaseThe acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease
Template:ABSTRACT PUBMED 22047104
About this StructureAbout this Structure
3rik is a 4 chain structure of Acid-beta-glucosidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Orwig SD, Tan YL, Grimster NP, Yu Z, Powers ET, Kelly JW, Lieberman RL. Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-beta-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease. Biochemistry. 2011 Dec 13;50(49):10647-57. Epub 2011 Nov 14. PMID:22047104 doi:10.1021/bi201619z