2brg: Difference between revisions

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{{Seed}}
[[Image:2brg.png|left|200px]]
[[Image:2brg.png|left|200px]]


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{{STRUCTURE_2brg|  PDB=2brg  |  SCENE=  }}  
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===STRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITY===
===STRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITY===


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{{ABSTRACT_PUBMED_15974586}}


==About this Structure==
==About this Structure==
2BRG is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRG OCA].  
[[2brg]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRG OCA].  
 
==See Also==
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15974586</ref><references group="xtra"/>
<ref group="xtra">PMID:015974586</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Oncology]]
[[Category: Oncology]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Polymorphism]]
[[Category: Pyrrolopyrimidine]]
[[Category: Pyrrolopyrimidine]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:31:13 2009''

Revision as of 03:24, 27 July 2012

File:2brg.png

Template:STRUCTURE 2brg

STRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITYSTRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITY

Template:ABSTRACT PUBMED 15974586

About this StructureAbout this Structure

2brg is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Foloppe N, Fisher LM, Howes R, Kierstan P, Potter A, Robertson AG, Surgenor AE. Structure-based design of novel Chk1 inhibitors: insights into hydrogen bonding and protein-ligand affinity. J Med Chem. 2005 Jun 30;48(13):4332-45. PMID:15974586 doi:10.1021/jm049022c

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