1fka: Difference between revisions

Revision as of 13:39, 21 February 2008

STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION

OverviewOverview

The small ribosomal subunit performs the decoding of genetic information during translation. The structure of that from Thermus thermophilus shows that the decoding center, which positions mRNA and three tRNAs, is constructed entirely of RNA. The entrance to the mRNA channel will encircle the message when a latch-like contact closes and contributes to processivity and fidelity. Extended RNA helical elements that run longitudinally through the body transmit structural changes, correlating events at the particle's far end with the cycle of mRNA translocation at the decoding region. 96% of the nucleotides were traced and the main fold of all proteins was determined. The latter are either peripheral or appear to serve as linkers. Some may assist the directionality of translocation.

About this StructureAbout this Structure

1FKA is a Protein complex structure of sequences from Thermus thermophilus with as ligand. The following page contains interesting information on the relation of 1FKA with [Ribosome]. Full crystallographic information is available from OCA.

ReferenceReference

Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution., Schluenzen F, Tocilj A, Zarivach R, Harms J, Gluehmann M, Janell D, Bashan A, Bartels H, Agmon I, Franceschi F, Yonath A, Cell. 2000 Sep 1;102(5):615-23. PMID:11007480

Page seeded by OCA on Thu Feb 21 12:39:34 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1fka.gif|left|200px]]<br />
+[[Image:1fka.gif|left|200px]]<br /><applet load="1fka" size="350" color="white" frame="true" align="right" spinBox="true"
-<applet load="1fka" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="1fka, resolution 3.30&Aring;" />
 '''STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION'''<br />
 ==Overview==
-The small ribosomal subunit performs the decoding of genetic information, during translation. The structure of that from Thermus thermophilus shows, that the decoding center, which positions mRNA and three tRNAs, is, constructed entirely of RNA. The entrance to the mRNA channel will, encircle the message when a latch-like contact closes and contributes to, processivity and fidelity. Extended RNA helical elements that run, longitudinally through the body transmit structural changes, correlating, events at the particle's far end with the cycle of mRNA translocation at, the decoding region. 96% of the nucleotides were traced and the main fold, of all proteins was determined. The latter are either peripheral or appear, to serve as linkers. Some may assist the directionality of translocation.
+The small ribosomal subunit performs the decoding of genetic information during translation. The structure of that from Thermus thermophilus shows that the decoding center, which positions mRNA and three tRNAs, is constructed entirely of RNA. The entrance to the mRNA channel will encircle the message when a latch-like contact closes and contributes to processivity and fidelity. Extended RNA helical elements that run longitudinally through the body transmit structural changes, correlating events at the particle's far end with the cycle of mRNA translocation at the decoding region. 96% of the nucleotides were traced and the main fold of all proteins was determined. The latter are either peripheral or appear to serve as linkers. Some may assist the directionality of translocation.
 ==About this Structure==
-FKA is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with WO2 as [http://en.wikipedia.org/wiki/ligand ligand]. The following page contains interesting information on the relation of 1FKA with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb10_1.html Ribosome]]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1FKA OCA].
+FKA is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=WO2:'>WO2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. The following page contains interesting information on the relation of 1FKA with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb10_1.html Ribosome]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FKA OCA].
 ==Reference==
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 [[Category: protein-rna complex]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 18 09:00:16 2007''
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