2fle: Difference between revisions

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{{Seed}}
[[Image:2fle.png|left|200px]]
[[Image:2fle.png|left|200px]]


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{{STRUCTURE_2fle|  PDB=2fle  |  SCENE=  }}  
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===Structural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutant===
===Structural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutant===


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{{ABSTRACT_PUBMED_18215016}}
{{ABSTRACT_PUBMED_18215016}}


==About this Structure==
==About this Structure==
2FLE is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FLE OCA].  
[[2fle]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FLE OCA].  
 
==See Also==
*[[Virus protease|Virus protease]]


==Reference==
==Reference==
<ref group="xtra">PMID:18215016</ref><references group="xtra"/>
<ref group="xtra">PMID:018215016</ref><references group="xtra"/>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Clemente, J C.]]
[[Category: Clemente, J C.]]
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[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Resistance]]
[[Category: Resistance]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 24 08:24:31 2010''

Revision as of 00:40, 27 July 2012

File:2fle.png

Template:STRUCTURE 2fle

Structural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutantStructural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutant

Template:ABSTRACT PUBMED 18215016

About this StructureAbout this Structure

2fle is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Clemente JC, Robbins A, Grana P, Paleo MR, Correa JF, Villaverde MC, Sardina FJ, Govindasamy L, Agbandje-McKenna M, McKenna R, Dunn BM, Sussman F. Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation. J Med Chem. 2008 Feb 28;51(4):852-60. Epub 2008 Jan 24. PMID:18215016 doi:10.1021/jm701170f

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